Wednesday 28 August 2013

The Contribution of Apathy and Increased Learning Trials to Risky Decision-Making in Parkinson's Disease

Arch Clin Neuropsychol. 2013 Aug 21. [Epub ahead of print]
Buelow MT, Frakey LL, Grace J, Friedman JH.

Source
Department of Psychology, The Ohio State University Newark, Newark, OH, USA.

Abstract

Impairments in executive functioning are commonly found in Parkinson's disease (PD); however, the research into risky decision making has been mixed. The present study sought to investigate three potential hypotheses: difficulty learning the task probabilities, levodopa equivalent dose (LED), and the presence of apathy. Twenty-four individuals with idiopathic PD and 13 healthy controls completed the Frontal Systems Behavior Scale to assess current apathy, the Iowa Gambling Task, and the Balloon Analog Risk Task (BART). Results indicated that individuals with PD selected more from Deck B, a disadvantageous deck. However, with an additional set of trials, participants with PD and apathy selected more from the most risky deck (Deck A). Apathy was not related to the BART, and LED was not related to either task. Results indicate that apathy is associated with decision-making in PD, and providing additional learning trials can improve decision-making in PD without apathy.

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