One needs to be a little bit cautious with this questionnaire, which suggests pRBD in up to 15% of healthy controls too...nonetheless the prevalence in this study of PD subjects does appear in line with what other studies have reported recently - cross sectional prevalence of about 30%...remember RBD can only really be diagnosed using polysomnography...
Eur J Neurol. 2015 Apr 22. doi: 10.1111/ene.12723. [Epub ahead of print]
Bjørnarå KA, Dietrichs E, Toft M.
BACKGROUND AND PURPOSE:
Rapid eye movement (REM) sleep behaviour disorder (RBD) is frequently present in patients with Parkinson's disease (PD) and may have prognostic implications. There are few longitudinal studies of RBD in patients with PD. Our aim was to investigate whether RBD was a persistent feature in a follow-up study of 107 patients with PD.
METHODS:
After a mean follow-up time of 3 years, 96 patients were available for reassessment. Probable RBD (pRBD) was diagnosed by the REM sleep behaviour disorder screening questionnaire.
RESULTS:
At follow-up, pRBD was found in 49% of the patients, versus 38% at baseline. The pRBD status remained unchanged in three-quarters of the patients, whilst 17% had new pRBD symptoms. Disease duration was longer in the pRBD group, 9.4 vs. 7.6 years (P = 0.02).
CONCLUSIONS:
Probable RBD is a persistent feature in PD and probably increases over time.
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