This is a new review by a colleague Ruth Dobson on bone health in PD and multiple sclerosis... she and I have previously co-authored a few articles on this topic... bone fracture is a major reason for people with PD to be admitted to hospital and a cause of deterioration physcially and in terms of symptom control. As is often the case, prevention is better than cure, so one should always be mindful of the risk of fracture in PD patients.... and start bone protection therapy where necessary.
Curr Osteoporos Rep. 2016 Aug 15. [Epub ahead of print]
Binks S, Dobson R.
Metabolic bone disease is a major public health concern, especially when it manifests as hip fracture which carries significant morbidity and mortality. Individuals with neurological disease are at higher risk of osteopenia, osteoporosis and fragility fracture compared to age-matched controls, yet this is under-appreciated by these patients. Clinician attention to this topic is therefore of importance and should address the bone health of men as well as women, a group in whom it may be an under-recognised problem. Evidence for optimal management of bone health in neurological disease remains to be defined, but a growing literature provides some useful guidance. This review focuses on two conditions, multiple sclerosis and Parkinson's disease, where research has been active over recent years. In neuroinflammation, shared immunological pathways between bone and brain are a current domain of interest and it will be intriguing to interrogate the action of emerging immunotherapies on these dual compartments.
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