Mullin S, Schapira A. The genetics of Parkinson's disease. Br Med Bull. 2015
May 20. pii: ldv022. [Epub ahead of print] PubMed PMID: 25995343.

http://bmb.oxfordjournals.org/content/early/2015/05/20/bmb.ldv022.short?rss=1

Only 15 years ago in medical school Parkinson’s disease was said to be the very definition of a non genetically inherited disease. It’s taken a giant leap forward in our understanding of genetics to realise that, as is the case in Parkinson’s, genetic inheritance doesn’t have mean one gene giving rise to a disease, but rather many genes, modified possibly by environmental factors or even one another, interacting to cause it. This article describes the genetic causes which account for 30% or so of the inheritance of Parkinson’s disease and speculates on what underlies the 70% of genetic inheritance which is still unclear.