J Clin Psychol Med Settings. 2012 May 12. [Epub ahead of print]
Delaney M, Leroi I, Simpson J, Overton PG.
Abstract
Parkinson's
disease (PD) is a progressive neurodegenerative disease primarily
characterised by motor symptoms. However, another feature of PD which
is receiving increasing attention is the phenomenon of impulse control
disorders (ICDs), such as pathological gambling. To date, research into
ICDs in PD has centred on a biomedical model of cause, related to the
effects of dopamine replacement therapy. However, there are several
areas of discrepancy in the current biomedical account of ICDs in PD.
In addition, we argue that social and psychological factors also need
to be considered to achieve a more complete understanding of the
phenomenon. We present a novel conceptual model which combines
biomedical and psychosocial factors in the genesis of ICDs in PD and
use the model to identify a number of potential treatment intervention
points and to highlight important outstanding questions concerning the
inter-relationship between psychosocial and biomedical factors in the
genesis of ICDs in PD.
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