Enlarged substantia nigra hyperechogenicity and risk for Parkinson disease: a 37-month 3-center study of 1847 older persons.
Berg D, Seppi K, Behnke S, Liepelt I, Schweitzer K, Stockner H, Wollenweber F, Gaenslen A, Mahlknecht P, Spiegel J, Godau J, Huber H, Srulijes K, Kiechl S, Bentele M, Gasperi A, Schubert T, Hiry T, Probst M, Schneider V, Klenk J, Sawires M, Willeit J, Maetzler W, Fassbender K, Gasser T, Poewe W.
Arch Neurol. 2011;68(7):932-937. doi:10.1001/archneurol.2011.141
"These are the emerging data from the novel PRIPS study taking place in Germany and Austria, which looks at markers for early Parkinson's disease. This article shows how ultrasound scanning of brain structure through the temple of the head can be used to identify people at increased risk of Parkinson's. Whilst there are some problems with this technology, such as it cannot be used in 10% of people due to differences in skull bones, this report underlines the potential for this technique in predicting Parkinson's. It is a cheaper and simpler imaging technique than other imaging options that look to achieve the same thing."
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